Watermelon is very susceptible to pests and diseases, especially aphids’ proper cultural management practices on pests and diseases shall be explored to obtain a high yield. Thus, the study was conducted to evaluate the efficacy of radish extract in controlling insect pests in watermelon. Specifically, this study aimed to determine; the best mode and rate of application of radish extract in the control of pest in watermelon; Interaction effects between mode and rate of application of radish extract in controlling insect pest in watermelon; Evaluate the sugar content of watermelon, Profitability of radish extract as pesticide control in watermelon. The research study was laid out following Randomized Complete Block Design (RCBD) with three replications. Analysis of variance (ANOVA) was used, and Scheffe Test was done for significant results. Based on the results of the study on the growth of watermelon, drenching and spraying as modes of application for insect pest control can both be used. The use of a high concentration of radish extract (350 ml) mixed with 16 liters of water can be used as pest control, as this was comparable to Actara, a commercial insecticide. For sweeter watermelon and high yield, use 300 ml radish extract mixed with 16 liters of water. It is recommended that a higher concentration of radish extract be explored for its potential as insect pest control for other cucurbits.