Terpenoids from Tithonia diversifolia
Consolacion Y. Ragasa | Myrna Tepora | John A. Rideout
Discipline: Biochemistry
Abstract:
The air-dried flowers of Tithonia diversifolia, commonly known as native sunflower, afforded tagitinin C (1), fatty acid esters of faradiol (2), squalene (3), and a mixture (1:2) of stigmasterol (4) and sitosterol (5). The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy, while the structures of 2 to 5were deduced by a comparison of their 1H and 13C NMR spectral data with those found in the literature. Antimicrobial tests on 1 indicated that it was moderately active against S. aureus and C. albicans; slightly active against E. coli, P. aeruginosa, and T. mentagrophytes; and inactive against B. subtilis and A. niger.
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